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United States FDA / DSHEA Lens DSHEA dietary supplement pathway alignment NDI notification risk assessment (novel liposomal systems, unusual carriers, aggressive dose stories) GRAS / established-ingredient status checks where relevant Supplement Facts compliance and structure/function claim boundaries Early ingredient screening reduces NDI exposure and keeps US launch paths DSHEA-defensible
Bianchi G, Giusti A, Pioli G, Barone A, Palummeri E, Girasole G
When these demands exceed available biochemical reserve, mitochondrial energy and recovery from stress may become less efficient
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